So for one of the most common genetic diseases, Sickle cell is far from the most researched. However, incredibly scientists found that the cause of death of the famous Egyptian King Tutankhamen, was actually Sickle cell disease and not malaria as suspected previously. That would date one of the first records of Sickle to be in 1300 BC!! Death at a young age was common back then, but how many more deaths were accelerated because of Sickle Cell? With the living conditions we can only imagine how the intense heat and environment could have affected him and many others sickle cell.